Cyp2c70-KO 基因敲除小鼠

1. de Vries, Hilde D, Palmiotti, Anna, Li, Rumei, Kuipers, Folkert, de Boer, Jan Freark. 2022. Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids. In Pediatric research, 93, 1582-1590. doi:10.1038/s41390-022-02303-5. https://pubmed.ncbi.nlm.nih.gov/36151295/

2. Truong, Jennifer K, Bennett, Ashley L, Klindt, Caroline, Dawson, Paul A, Karpen, Saul J. 2022. Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury. In Journal of lipid research, 63, 100261. doi:10.1016/j.jlr.2022.100261. https://pubmed.ncbi.nlm.nih.gov/35934110/

3. de Vries, Hilde D, Eijgenraam, Tim R, Bloks, Vincent W, Kuipers, Folkert, de Boer, Jan Freark. 2024. Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70-/- mice. In Pediatric research, , . doi:10.1038/s41390-024-03596-4. https://pubmed.ncbi.nlm.nih.gov/39358409/