Rin3-KO 基因敲除小鼠

1. Meshref, Mostafa, Ghaith, Hazem S, Hammad, Mohamed Ahmed, Shalash, Ali, Bahbah, Eshak I. 2023. The Role of RIN3 Gene in Alzheimer's Disease Pathogenesis: a Comprehensive Review. In Molecular neurobiology, 61, 3528-3544. doi:10.1007/s12035-023-03802-0. https://pubmed.ncbi.nlm.nih.gov/37995081/

2. Karch, Celeste M, Goate, Alison M. 2014. Alzheimer's disease risk genes and mechanisms of disease pathogenesis. In Biological psychiatry, 77, 43-51. doi:10.1016/j.biopsych.2014.05.006. https://pubmed.ncbi.nlm.nih.gov/24951455/

3. Shen, Ruinan, Zhao, Xiaobei, He, Lu, Ding, Jianqing, Wu, Chengbiao. 2020. Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease. In Translational neurodegeneration, 9, 26. doi:10.1186/s40035-020-00206-1. https://pubmed.ncbi.nlm.nih.gov/32552912/

4. Zhou, Xuan, Yu, Lili, Wang, Lijuan, Theodoratou, Evropi, Li, Xue. 2022. Alcohol consumption, blood DNA methylation and breast cancer: a Mendelian randomisation study. In European journal of epidemiology, 37, 701-712. doi:10.1007/s10654-022-00886-1. https://pubmed.ncbi.nlm.nih.gov/35708873/

5. Shen, Ruinan, Murphy, Caitlin J, Xu, Xiaowen, Ding, Jianqing, Wu, Chengbiao. 2022. Ras and Rab Interactor 3: From Cellular Mechanisms to Human Diseases. In Frontiers in cell and developmental biology, 10, 824961. doi:10.3389/fcell.2022.824961. https://pubmed.ncbi.nlm.nih.gov/35359443/

6. Tesi, Niccolo', van der Lee, Sven, Hulsman, Marc, Reinders, Marcel, Holstege, Henne. 2024. Cognitively healthy centenarians are genetically protected against Alzheimer's disease. In Alzheimer's & dementia : the journal of the Alzheimer's Association, 20, 3864-3875. doi:10.1002/alz.13810. https://pubmed.ncbi.nlm.nih.gov/38634500/

7. Holstege, Henne, Hulsman, Marc, Charbonnier, Camille, Bellenguez, Céline, Lambert, Jean-Charles. 2022. Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease. In Nature genetics, 54, 1786-1794. doi:10.1038/s41588-022-01208-7. https://pubmed.ncbi.nlm.nih.gov/36411364/

8. De Ridder, Raphaël, Boudin, Eveline, Vandeweyer, Geert, Mortier, Geert, Van Hul, Wim. 2019. Genetic Variation in RIN3 in the Belgian Population Supports Its Involvement in the Pathogenesis of Paget's Disease of Bone and Modifies the Age of Onset. In Calcified tissue international, 104, 613-621. doi:10.1007/s00223-019-00530-3. https://pubmed.ncbi.nlm.nih.gov/30726512/

9. Vallet, Mahéva, Sophocleous, Antonia, Törnqvist, Anna E, Albagha, Omar Me, Ralston, Stuart H. 2021. Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation. In Calcified tissue international, 109, 92-102. doi:10.1007/s00223-021-00827-2. https://pubmed.ncbi.nlm.nih.gov/33725152/

10. Miao, Meng, Yuan, Fang, Ma, Xiaotian, Zhu, Zhengyu, Bi, Jianzhong. 2021. Methylation of the RIN3 Promoter is Associated with Transient Ischemic Stroke/Mild Ischemic Stroke with Early Cognitive Impairment. In Neuropsychiatric disease and treatment, 17, 2587-2598. doi:10.2147/NDT.S320167. https://pubmed.ncbi.nlm.nih.gov/34408420/