Ppp1ca-KO 基因敲除小鼠

1. Chen, Zhenzhou, Li, Yidan, He, Kuan, Chen, Yajun, Fu, Zhongxue. 2023. CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation. In Journal of experimental & clinical cancer research : CR, 42, 334. doi:10.1186/s13046-023-02915-7. https://pubmed.ncbi.nlm.nih.gov/38057879/

2. Zhang, Lu, Jiao, Guangjun, You, Yunhao, Meng, Chunyang, Chen, Yunzhen. . Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation. In Clinical and translational medicine, 13, e1369. doi:10.1002/ctm2.1369. https://pubmed.ncbi.nlm.nih.gov/37649137/

3. Zhang, Zhen, Wang, Zi-Xian, Chen, Yan-Xing, Qiu, Miao-Zhen, Xu, Rui-Hua. 2022. Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response. In Genome medicine, 14, 45. doi:10.1186/s13073-022-01050-w. https://pubmed.ncbi.nlm.nih.gov/35488273/

4. Sun, Hongze, Ou, Baochi, Zhao, Senlin, Wang, Rangrang, Peng, Zhihai. 2019. USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway. In EBioMedicine, 48, 236-247. doi:10.1016/j.ebiom.2019.08.061. https://pubmed.ncbi.nlm.nih.gov/31521612/

5. Huang, Bo, Ren, Junwu, Ma, Qiang, Wang, Yongquan, Xiao, Bin. 2024. A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway. In Molecular cancer, 23, 34. doi:10.1186/s12943-024-01940-0. https://pubmed.ncbi.nlm.nih.gov/38360682/

6. Grimm, P Richard, Tatomir, Anamaria, Rosenbaek, Lena L, Fenton, Robert A, Welling, Paul A. 2023. Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure. In The Journal of clinical investigation, 133, . doi:10.1172/JCI158498. https://pubmed.ncbi.nlm.nih.gov/37676724/

7. Hsu, L-C, Huang, X, Seasholtz, S, Potter, D M, Gollin, S M. 2006. Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines. In Oncogene, 25, 5517-26. doi:. https://pubmed.ncbi.nlm.nih.gov/16619035/

8. Silva, Joana V, Freitas, Maria J, Fardilha, Margarida. . Phosphoprotein phosphatase 1 complexes in spermatogenesis. In Current molecular pharmacology, 7, 136-46. doi:. https://pubmed.ncbi.nlm.nih.gov/25620225/

9. Huang, Yiqiao, Cen, Yi, Wu, Hualing, Jiang, Xianhan, Wei, Anyang. . Nodularin-R Synergistically Enhances Abiraterone Against Castrate- Resistant Prostate Cancer via PPP1CA Inhibition. In Journal of cellular and molecular medicine, 28, e70210. doi:10.1111/jcmm.70210. https://pubmed.ncbi.nlm.nih.gov/39550701/