智鼠故事 
Capn1-KO 基因敲除小鼠
复苏/繁育服务
产品名称
Capn1-KO 基因敲除小鼠
产品编号
S-KO-01316
品系全称
C57BL/6NCya-Capn1em1/Cya
品系背景
C57BL/6NCya
品系编号
KOCMP-12333-Capn1-B6N-VA
品系状态
使用本品系发表的文献需注明： Capn1-KO 基因敲除小鼠 mice (Strain S-KO-01316) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
Capa1，Capa-1，mu-calpin
NCBI ID
染色体号
Chr 19
NCBI RefSeq
NM_007600
Ensembl ID
ENSMUST00000025891
修饰方式
全身性基因敲除
靶向范围
Exon 4~7
敲除长度
~4.6 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:88263Animals homozygous for a mutation of this gene exhibit decreased platelet aggregation and defective clot retraction although bleeding times remain similar to wild-type.
发表文献
Journal of Ginseng Research
2024-03-11
Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/STAT3 signaling pathway
Heliyon
2023-11-29
Baicalin attenuates pulmonary vascular remodeling by inhibiting calpain-1 mediated endothelial-to-mesenchymal transition
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
2022-02-27
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension
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