Dguok 深入了解基因-突变-疾病-模型全维度数据，尽在Rare Disease Data Center（RDDC）综合数据库

MGI:1351602 Mice homozygous for a knock-out allele exhibit weight loss, absent subcutaneous fat tissue, severe mtDNA depletion and mitochondrial dysfunction in the liver with signs of oxidative stress, liver damage and regeneration, increased catabolic lipid metabolism, and a progressive change in fur color.