智鼠故事 
C57BL/6JCya-Caskem1flox/Cya 条件性基因敲除小鼠
复苏/繁育服务
产品名称
Cask-flox
产品编号
S-CKO-19486
品系全称
C57BL/6JCya-Caskem1flox/Cya
品系背景
C57BL/6JCya
品系编号
CKOCMP-12361-Cask-B6J-VB
品系状态
使用本品系发表的文献需注明： Cask-flox mice (Strain S-CKO-19486) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
LIN-2，Pals3，DXPri1，DXRib1，mLin-2
NCBI ID
染色体号
Chr X
NCBI RefSeq
NM_001284505
Ensembl ID
ENSMUST00000115438
修饰方式
条件性基因敲除
靶向范围
Exon 6
敲除长度
~1.7 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:1309489Mutation of this gene results in cleft palate and perinatal lethality in hemizygous males and death within 2 weeks in females on a C57BL/6J background. Some female animals on a CD1 background survive to adulthood exhibiting patchy fur, wrinkled skin, a kinked tail and spine, and give birth to small and infrequent litters. Male and female animals on all genetic backgrounds exhibit reduced head size, shortened jaw, and a pointed snout.
