Polb-flox 基因敲除小鼠

1. Tan, Xiaohui, Wang, Hongyi, Luo, Guangbin, Fu, Sidney W, Lu, Youyong. 2015. Clinical significance of a point mutation in DNA polymerase beta (POLB) gene in gastric cancer. In International journal of biological sciences, 11, 144-55. doi:10.7150/ijbs.10692. https://pubmed.ncbi.nlm.nih.gov/25561897/

2. Donigan, Katherine A, Sun, Ka-wai, Nemec, Antonia A, Zelterman, Daniel, Sweasy, Joann B. 2012. Human POLB gene is mutated in high percentage of colorectal tumors. In The Journal of biological chemistry, 287, 23830-9. doi:10.1074/jbc.M111.324947. https://pubmed.ncbi.nlm.nih.gov/22577134/

3. Qiu, Z, Goodman, M F. . The Escherichia coli polB locus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from a polB mutant. In The Journal of biological chemistry, 272, 8611-7. doi:. https://pubmed.ncbi.nlm.nih.gov/9079692/

4. Senejani, Alireza G, Liu, Yanfeng, Kidane, Dawit, Bothwell, Alfred L M, Sweasy, Joann B. 2014. Mutation of POLB causes lupus in mice. In Cell reports, 6, 1-8. doi:10.1016/j.celrep.2013.12.017. https://pubmed.ncbi.nlm.nih.gov/24388753/

5. Chakravarty, Shubham, Ramos-Hegazy, Layla, Gasparovic, Abigail, Anderson, Gregory G. 2020. DNA alternate polymerase PolB mediates inhibition of type III secretion in Pseudomonas aeruginosa. In Microbes and infection, 23, 104777. doi:10.1016/j.micinf.2020.11.004. https://pubmed.ncbi.nlm.nih.gov/33276123/