Reg2-flox 基因敲除小鼠

1. Frederick, D L, Tatchell, K. . The REG2 gene of Saccharomyces cerevisiae encodes a type 1 protein phosphatase-binding protein that functions with Reg1p and the Snf1 protein kinase to regulate growth. In Molecular and cellular biology, 16, 2922-31. doi:. https://pubmed.ncbi.nlm.nih.gov/8649403/

2. Li, Qing, Li, Bing, Miao, Xiaoliang, Gao, Zu-Hua, Liu, Jun-Li. . Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet-Induced Obesity. In Endocrinology, 158, 1634-1644. doi:10.1210/en.2016-1551. https://pubmed.ncbi.nlm.nih.gov/28009527/

3. Yun, Jun-Won, Zhao, Zeping, Yan, Xi, Vatamaniuk, Marko Z, Lei, Xin Gen. 2019. Glutathione peroxidase-1 inhibits transcription of regenerating islet-derived protein-2 in pancreatic islets. In Free radical biology & medicine, 134, 385-393. doi:10.1016/j.freeradbiomed.2019.01.024. https://pubmed.ncbi.nlm.nih.gov/30703484/

4. Lieu, Hanh-Tu, Simon, Marie-Thérèse, Nguyen-Khoa, Thao, Bréchot, Christian, Christa, Laurence. . Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice. In Hepatology (Baltimore, Md.), 44, 1452-64. doi:. https://pubmed.ncbi.nlm.nih.gov/17133485/