Ubr7-flox 基因敲除小鼠

1. Adhikari, Swagata, Singh, Vipin, Nandi, Sandhik, Notani, Dimple, Das, Chandrima. 2024. UBR7 in concert with EZH2 inhibits the TGF-β signaling leading to extracellular matrix remodeling. In Cell reports, 43, 114394. doi:10.1016/j.celrep.2024.114394. https://pubmed.ncbi.nlm.nih.gov/38923455/

2. Feng, Maoxiao, Jiao, Qinlian, Ren, Yidan, Zhao, Miaoqing, Bi, Lei. 2024. The interaction between UBR7 and PRMT5 drives PDAC resistance to gemcitabine by regulating glycolysis and immune microenvironment. In Cell death & disease, 15, 758. doi:10.1038/s41419-024-07145-z. https://pubmed.ncbi.nlm.nih.gov/39424627/

3. Shi, Junxia, Zhou, Junxian, Jiang, Fan, Li, Zhihong, Zhu, Shuifang. 2023. The effects of the E3 ubiquitin-protein ligase UBR7 of Frankliniella occidentalis on the ability of insects to acquire and transmit TSWV. In PeerJ, 11, e15385. doi:10.7717/peerj.15385. https://pubmed.ncbi.nlm.nih.gov/37187513/

4. Li, Benchang, Zhou, Yafei, Che, Fengyu, Wang, Guoxia, Yang, Ying. 2023. Establishment of a novel human induced pluripotent stem cell line (SIPDi001-A) with compound heterozygous mutations in the UBR7 gene from a Li-Campeau syndrome patient. In Stem cell research, 71, 103165. doi:10.1016/j.scr.2023.103165. https://pubmed.ncbi.nlm.nih.gov/37478672/

5. Singh, Vipin, Mondal, Atanu, Adhikary, Santanu, Roy, Siddhartha, Das, Chandrima. 2024. UBR7 E3 Ligase Suppresses Interferon-β Mediated Immune Signaling by Targeting Sp110 in Hepatitis B Virus-Induced Hepatocellular Carcinoma. In ACS infectious diseases, 10, 3775-3796. doi:10.1021/acsinfecdis.4c00213. https://pubmed.ncbi.nlm.nih.gov/38938101/

6. Li, Chunmei, Beauregard-Lacroix, Eliane, Kondratev, Christine, Leroux, Michel R, Campeau, Philippe M. 2020. UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism. In American journal of human genetics, 108, 134-147. doi:10.1016/j.ajhg.2020.11.018. https://pubmed.ncbi.nlm.nih.gov/33340455/

7. Adhikary, Santanu, Chakravarti, Deepavali, Terranova, Christopher, Rai, Kunal, Das, Chandrima. 2019. Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor. In Nature communications, 10, 1398. doi:10.1038/s41467-019-08986-5. https://pubmed.ncbi.nlm.nih.gov/30923315/

8. Zimmerman, Shawn W, Yi, Young-Joo, Sutovsky, Miriam, Conant, Gavin, Sutovsky, Peter. 2014. Identification and characterization of RING-finger ubiquitin ligase UBR7 in mammalian spermatozoa. In Cell and tissue research, 356, 261-78. doi:10.1007/s00441-014-1808-x. https://pubmed.ncbi.nlm.nih.gov/24664117/