Lpar2-flox 基因敲除小鼠

1. Sun, Kai, Chen, Ri-Xin, Li, Jing-Zhang, Luo, Zhan-Xiong. 2022. LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma. In Hereditas, 159, 16. doi:10.1186/s41065-022-00229-w. https://pubmed.ncbi.nlm.nih.gov/35241179/

2. Zhang, Runan, Liu, Yufang, Li, Wentao, Chu, Mingxing, Wang, Linjie. 2024. A mutation in LPAR2 activates the miR-939-5p-LPAR2-PI3K/AKT axis to regulate the proliferation and apoptosis of granulosa cells in sheep. In Theriogenology, 219, 1-10. doi:10.1016/j.theriogenology.2024.02.010. https://pubmed.ncbi.nlm.nih.gov/38368704/

3. Ara, Hosne, Subedi, Utsab, Sharma, Papori, Miriyala, Sumitra, Panchatcharam, Manikandan. 2022. Alteration of Cellular Energy Metabolism through LPAR2-Axin2 Axis in Gastric Cancer. In Biomolecules, 12, . doi:10.3390/biom12121805. https://pubmed.ncbi.nlm.nih.gov/36551233/

4. Fischer, Caroline, Schreiber, Yannick, Nitsch, Robert, Geisslinger, Gerd, Tegeder, Irmgard. 2024. Lysophosphatidic Acid Receptors LPAR5 and LPAR2 Inversely Control Hydroxychloroquine-Evoked Itch and Scratching in Mice. In International journal of molecular sciences, 25, . doi:10.3390/ijms25158177. https://pubmed.ncbi.nlm.nih.gov/39125747/

5. Wu, Wenhua, Chen, Zhengrui, Wen, Haiteng, Zhang, Haiyun. 2024. Unveiling potential drug targets for lung squamous cell carcinoma through the integration of druggable genome and genome-wide association data. In Frontiers in genetics, 15, 1431684. doi:10.3389/fgene.2024.1431684. https://pubmed.ncbi.nlm.nih.gov/39175755/

6. Benesch, Matthew Gk, Wu, Rongrong, Rog, Colin J, Ishikawa, Takashi, Takabe, Kazuaki. 2024. Insights into autotaxin- and lysophosphatidate-mediated signaling in the pancreatic ductal adenocarcinoma tumor microenvironment: a survey of pathway gene expression. In American journal of cancer research, 14, 4004-4027. doi:10.62347/KQNW1871. https://pubmed.ncbi.nlm.nih.gov/39267662/

7. Lin, Songbai, Lee, Sei-Jung, Shim, Hyunsuk, Chun, Jerold, Yun, C Chris. 2010. The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine. In American journal of physiology. Gastrointestinal and liver physiology, 299, G1128-38. doi:10.1152/ajpgi.00321.2010. https://pubmed.ncbi.nlm.nih.gov/20724530/

8. Shukla, Pradeep K, Meena, Avtar S, Gangwar, Ruchika, Tigyi, Gabor, Rao, RadhaKrishna. 2020. LPAR2 receptor activation attenuates radiation-induced disruption of apical junctional complexes and mucosal barrier dysfunction in mouse colon. In FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34, 11641-11657. doi:10.1096/fj.202000544R. https://pubmed.ncbi.nlm.nih.gov/32654268/

9. Benesch, Matthew G K, Wu, Rongrong, Tang, Xiaoyun, Ishikawa, Takashi, Takabe, Kazuaki. 2023. Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression. In International journal of molecular sciences, 24, . doi:10.3390/ijms24129812. https://pubmed.ncbi.nlm.nih.gov/37372960/

10. Shida, Dai, Inoue, Satoru, Yoshida, Yuki, Tsuji, Tsutomu, Tsuiji, Makoto. . Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer. In World journal of gastroenterology, 22, 2503-11. doi:10.3748/wjg.v22.i8.2503. https://pubmed.ncbi.nlm.nih.gov/26937138/