Esyt2-flox 基因敲除小鼠

1. Herdman, Chelsea, Tremblay, Michel G, Mishra, Prakash K, Moss, Tom. . Loss of Extended Synaptotagmins ESyt2 and ESyt3 does not affect mouse development or viability, but in vitro cell migration and survival under stress are affected. In Cell cycle (Georgetown, Tex.), 13, 2616-25. doi:10.4161/15384101.2014.943573. https://pubmed.ncbi.nlm.nih.gov/25486202/

2. Zhao, Mengya, Jin, Yu, Yan, Zhongyi, Zhang, Yuan, Yao, Yao. 2024. The splicing factor QKI inhibits metastasis by modulating alternative splicing of E-Syt2 in papillary thyroid carcinoma. In Cancer letters, 604, 217270. doi:10.1016/j.canlet.2024.217270. https://pubmed.ncbi.nlm.nih.gov/39306227/

3. Whittle, Benjamin J, Izuogu, Osagie G, Lowes, Hannah, Santibanez-Koref, Mauro, Hudson, Gavin. 2024. Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression. In NPJ Parkinson's disease, 10, 25. doi:10.1038/s41531-024-00636-y. https://pubmed.ncbi.nlm.nih.gov/38245550/

4. Du, Wei, Li, Ying, Wang, Xufeng, Zheng, Yan, Jia, Huliang. 2024. Circular RNA circESYT2 serves as a microRNA-665 sponge to promote the progression of hepatocellular carcinoma through ENO2. In Cancer science, 115, 2659-2672. doi:10.1111/cas.16207. https://pubmed.ncbi.nlm.nih.gov/38710213/