Spink6-flox 基因敲除小鼠

1. Li, Zhuoqi, Zheng, Chunning, Liu, Hongtao, Zhang, Chi, Tian, Yuan. 2023. A novel oxidative stress-related gene signature as an indicator of prognosis and immunotherapy responses in HNSCC. In Aging, 15, 14957-14984. doi:10.18632/aging.205323. https://pubmed.ncbi.nlm.nih.gov/38157249/

2. Zhang, Xiyang, Wang, Jing, Liang, Xiaohua, Yang, Shuya, Yang, Kun. 2025. BAP31-ELAVL1-SPINK6 axis induces loss of cell polarity and promotes metastasis in hepatocellular carcinoma. In International journal of biological sciences, 21, 1632-1648. doi:10.7150/ijbs.102566. https://pubmed.ncbi.nlm.nih.gov/39990675/

3. Kim, Hyun Je, Shim, Joon Ho, Park, Ji-Hye, Yang, Jun-Mo, Lee, Dongyoun. 2021. Single-cell RNA sequencing of human nail unit defines RSPO4 onychofibroblasts and SPINK6 nail epithelium. In Communications biology, 4, 692. doi:10.1038/s42003-021-02223-w. https://pubmed.ncbi.nlm.nih.gov/34099859/

4. Xinyue, Zhang, Li, Siwei, Yujie, Wang, Changhao, Bi, Xueli, Zhang. 2024. Engineering of HEK293T Cell Factory for Lentiviral Production by High-Throughput Selected Genes. In The CRISPR journal, 7, 272-282. doi:10.1089/crispr.2024.0016. https://pubmed.ncbi.nlm.nih.gov/39387256/

5. Ge, Kuikui, Huang, Jinjiang, Wang, Wei, Zhong, Jiang, Huang, Qingshan. . Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action. In Oncotarget, 8, 5965-5975. doi:10.18632/oncotarget.13983. https://pubmed.ncbi.nlm.nih.gov/27999203/

6. Lu, Hairong, Huang, Jinjiang, Li, Guodong, Wu, Hongyu, Huang, Qingshan. 2011. Expression, purification and characterization of recombinant human serine proteinase inhibitor Kazal-type 6 (SPINK6) in Pichia pastoris. In Protein expression and purification, 82, 144-9. doi:10.1016/j.pep.2011.12.004. https://pubmed.ncbi.nlm.nih.gov/22212898/

7. Chang, Y Y, van der Velden, J, van der Wier, G, Zeeuwen, P L J M, Jonkman, M F. 2012. Keratolysis exfoliativa (dyshidrosis lamellosa sicca): a distinct peeling entity. In The British journal of dermatology, 167, 1076-84. doi:10.1111/j.1365-2133.2012.11175.x. https://pubmed.ncbi.nlm.nih.gov/23039091/

8. Nie, Qian, Cao, Huan, Yang, Jianwang, Liu, Tao, Wang, Baoshan. 2024. Integration RNA bulk and single cell RNA sequencing to explore the change of glycolysis-related immune microenvironment and construct prognostic signature in head and neck squamous cell carcinoma. In Translational oncology, 46, 102021. doi:10.1016/j.tranon.2024.102021. https://pubmed.ncbi.nlm.nih.gov/38850799/

9. Tian, Saisai, Meng, Guofeng, Zhang, Weidong. 2018. A six-mRNA prognostic model to predict survival in head and neck squamous cell carcinoma. In Cancer management and research, 11, 131-142. doi:10.2147/CMAR.S185875. https://pubmed.ncbi.nlm.nih.gov/30588115/

10. Fischer, J, Meyer-Hoffert, U. 2013. Regulation of kallikrein-related peptidases in the skin - from physiology to diseases to therapeutic options. In Thrombosis and haemostasis, 110, 442-9. doi:10.1160/TH12-11-0836. https://pubmed.ncbi.nlm.nih.gov/23446429/