Ezr-flox 基因敲除小鼠

1. Zhang, Rongju, Zhang, Shaohui, Xing, Rongge, Zhang, Qin. 2019. High expression of EZR (ezrin) gene is correlated with the poor overall survival of breast cancer patients. In Thoracic cancer, 10, 1953-1961. doi:10.1111/1759-7714.13174. https://pubmed.ncbi.nlm.nih.gov/31452341/

2. Xiao, Guodong, Cheng, Feng, Yuan, Jing, Wang, Peili, Fan, Huijie. 2022. Integrative multiomics analysis identifies a metastasis-related gene signature and the potential oncogenic role of EZR in breast cancer. In Oncology research, 30, 35-51. doi:10.32604/or.2022.026616. https://pubmed.ncbi.nlm.nih.gov/37304008/

3. Xu, Jian, Zhang, Wei. 2021. EZR promotes pancreatic cancer proliferation and metastasis by activating FAK/AKT signaling pathway. In Cancer cell international, 21, 521. doi:10.1186/s12935-021-02222-1. https://pubmed.ncbi.nlm.nih.gov/34627255/

4. García-Solís, Blanca, Van Den Rym, Ana, Martinez-Martínez, Laura, de la Calle-Martín, Oscar, Pérez de Diego, Rebeca. 2023. Inherited human ezrin deficiency impairs adaptive immunity. In The Journal of allergy and clinical immunology, 152, 997-1009.e11. doi:10.1016/j.jaci.2023.05.022. https://pubmed.ncbi.nlm.nih.gov/37301410/

5. Zhang, Xiao-Dan, Huang, Guo-Wei, Xie, Ying-Hua, Li, En-Min, Xu, Li-Yan. . The interaction of lncRNA EZR-AS1 with SMYD3 maintains overexpression of EZR in ESCC cells. In Nucleic acids research, 46, 1793-1809. doi:10.1093/nar/gkx1259. https://pubmed.ncbi.nlm.nih.gov/29253179/

6. Tabur, Suzan, Oztuzcu, Serdar, Oguz, Elif, Ozkaya, Mesut, Demiryürek, Abdullah T. 2016. Evidence for elevated (LIMK2 and CFL1) and suppressed (ICAM1, EZR, MAP2K2, and NOS3) gene expressions in metabolic syndrome. In Endocrine, 53, 465-70. doi:10.1007/s12020-016-0910-0. https://pubmed.ncbi.nlm.nih.gov/26956845/