Slit2-flox 基因敲除小鼠

1. Tavora, Bernardo, Mederer, Tobias, Wessel, Kai J, Goodarzi, Hani, Tavazoie, Sohail F. 2020. Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis. In Nature, 586, 299-304. doi:10.1038/s41586-020-2774-y. https://pubmed.ncbi.nlm.nih.gov/32999457/

2. Geraldo, Luiz H, Xu, Yunling, Jacob, Laurent, Eichmann, Anne, Mathivet, Thomas. . SLIT2/ROBO signaling in tumor-associated microglia and macrophages drives glioblastoma immunosuppression and vascular dysmorphia. In The Journal of clinical investigation, 131, . doi:10.1172/JCI141083. https://pubmed.ncbi.nlm.nih.gov/34181595/

3. Kim, Yujin, Lee, Bo Bin, Kim, Dongho, Shim, Young Mog, Kim, Duk-Hwan. 2022. Aberrant Methylation of SLIT2 Gene in Plasma Cell-Free DNA of Non-Small Cell Lung Cancer Patients. In Cancers, 14, . doi:10.3390/cancers14020296. https://pubmed.ncbi.nlm.nih.gov/35053460/

4. Li, Jinyu, Geraldo, Luiz Henrique, Dubrac, Alexandre, Zarkada, Georgia, Eichmann, Anne. 2021. Slit2-Robo Signaling Promotes Glomerular Vascularization and Nephron Development. In Journal of the American Society of Nephrology : JASN, 32, 2255-2272. doi:10.1681/ASN.2020111640. https://pubmed.ncbi.nlm.nih.gov/34341180/

5. Suvarna, Kruthi, Jayabal, Panneerselvam, Ma, Xiuye, Shiio, Yuzuru. 2022. Slit2 signaling stimulates Ewing sarcoma growth. In Genes & cancer, 13, 88-99. doi:10.18632/genesandcancer.227. https://pubmed.ncbi.nlm.nih.gov/36533189/

6. . . Mutations in Gene Coding for SLIT2 Linked to Preterm Birth: SLIT2 and its receptor ROBO1 are components of the signaling network that promotes spontaneous preterm birth. In American journal of medical genetics. Part A, 179, 1684-1685. doi:10.1002/ajmg.a.40459. https://pubmed.ncbi.nlm.nih.gov/31393085/