Gjb2-flox 基因敲除小鼠

1. Liu, Wei, Rask-Andersen, Helge. 2022. GJB2 and GJB6 gene transcripts in the human cochlea: A study using RNAscope, confocal, and super-resolution structured illumination microscopy. In Frontiers in molecular neuroscience, 15, 973646. doi:10.3389/fnmol.2022.973646. https://pubmed.ncbi.nlm.nih.gov/36204137/

2. Snoeckx, Rikkert L, Huygen, Patrick L M, Feldmann, Delphine, Smith, Richard J H, Van Camp, Guy. 2005. GJB2 mutations and degree of hearing loss: a multicenter study. In American journal of human genetics, 77, 945-57. doi:. https://pubmed.ncbi.nlm.nih.gov/16380907/

3. Miyagawa, Maiko, Naito, Takehiko, Nishio, Shin-ya, Kamatani, Naoyuki, Usami, Shin-ichi. 2013. Targeted exon sequencing successfully discovers rare causative genes and clarifies the molecular epidemiology of Japanese deafness patients. In PloS one, 8, e71381. doi:10.1371/journal.pone.0071381. https://pubmed.ncbi.nlm.nih.gov/23967202/

4. Mikstiene, Violeta, Jakaitiene, Audrone, Byckova, Jekaterina, Kucinskas, Vaidutis, Utkus, Algirdas. 2016. The high frequency of GJB2 gene mutation c.313_326del14 suggests its possible origin in ancestors of Lithuanian population. In BMC genetics, 17, 45. doi:10.1186/s12863-016-0354-9. https://pubmed.ncbi.nlm.nih.gov/26896187/

5. Richard, Elodie M, Santos-Cortez, Regie Lyn P, Faridi, Rabia, Leal, Suzanne M, Riazuddin, Saima. 2018. Global genetic insight contributed by consanguineous Pakistani families segregating hearing loss. In Human mutation, 40, 53-72. doi:10.1002/humu.23666. https://pubmed.ncbi.nlm.nih.gov/30303587/