智鼠故事 
C57BL/6NCya-Rhoaem1flox/Cya 条件性基因敲除小鼠
复苏/繁育服务
产品名称
Rhoa-flox
产品编号
S-CKO-01297
品系全称
C57BL/6NCya-Rhoaem1flox/Cya
品系背景
C57BL/6NCya
品系编号
CKOCMP-11848-Rhoa-B6N-VA
品系状态
使用本品系发表的文献需注明： Rhoa-flox mice (Strain S-CKO-01297) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
Arha，Arha1，Arha2
NCBI ID
染色体号
Chr 9
NCBI RefSeq
NM_016802
Ensembl ID
ENSMUST00000007959
修饰方式
条件性基因敲除
靶向范围
Exon 4
敲除长度
~1.2 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:1096342Mice homozygous for a conditional allele activated in neuroepithelial cells exhibit lethality during late embryonic stages associated with early cell cycle exit, premature neuronal precursor differentiation, increased apoptosis in the neural tube.
发表文献
Neural Regeneration Research
2023-12-01
Motor neuron-specific RhoA knockout delays degeneration and promotes regeneration of dendrites in spinal ventral horn after brachial plexus injury
Glia
2023-03-27
Schwann cell-specific RhoA knockout accelerates peripheral nerve regeneration via promoting Schwann cell dedifferentiation
Journal of Neuroinflammation
2021-10-15
Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice
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