智鼠故事 
B6-hSCN2A
复苏/繁育服务
HUGO-GT®全基因组人源化模型
* 使用本品系发表的文献需注明：B6-hSCN2A mice (Catalog I001131) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
只
品系描述
本模型为小鼠Scn2a基因的人源化模型，可用于癫痫的疾病机制研究和靶向药物的筛选及评估。该模型的纯合子是可存活且可育的。
相关疾病：
Seizures, Benign Familial Infantile, 3
Developmental and Epileptic Encephalopathy 11
Episodic Ataxia, Type 9
Benign Familial Infantile Epilepsy
West Syndrome
Malignant Migrating Focal Seizures of Infancy
Early Infantile Epileptic Encephalopathy
Scn2a Related Disorders
Episodic Ataxia
Hereditary Episodic Ataxia
Benign Familial Neonatal Epilepsy
Febrile Seizures
Benign Neonatal Seizures
Developmental and Epileptic Encephalopathy 30
Generalized Epilepsy with Febrile Seizures Plus
Dravet Syndrome
Non-Specific Syndromic Intellectual Disability
Autism
Autism Spectrum Disorder
Benign Epilepsy with Centrotemporal Spikes
Developmental and Epileptic Encephalopathy
Focal Epilepsy
Dystonia 12
Movement Disease
Spastic Ataxia
应用领域
癫痫（Epilepsy）
